College Football Week 10 Features High Stakes Ranked Rivalries
The Week 10 college football schedule includes six ranked matchups, with Notre Dame versus Miami and Utah versus BYU headlining a busy slate of games.
By Luca Harrison ·

The college football calendar reaches a pivotal point this week, featuring six matchups between ranked teams and nearly 60 total games across the nation. The schedule offers significant opportunities for fans and bettors to follow high-profile contests, with several games carrying major implications for the College Football Playoff. Notable matchups include a showdown between top ten opponents on Saturday, where No. 4 Notre Dame hosts No. 1 Miami at 7:30 p.m. ET. Earlier in the day, No. 3 Utah faces No. 7 BYU at noon ET in a highly anticipated regional rivalry.
Betting lines for the top games reflect close competition. Utah is listed as a 5.5-point favorite at home against BYU, with the total points set at 47.5. In the evening contest, Notre Dame is also a 5.5-point favorite at home against Miami, with the over/under line established at 57.5 points. These lines highlight the competitive nature of the current season, where seeding and conference standings remain fluid.
Other significant ranked matchups are scheduled for Saturday. No. 19 Missouri hosts No. 10 Texas at noon ET, with the Longhorns favored by 3 points and the total set at 43.5. In another SEC contest, No. 8 Kentucky visits No. 16 Tennessee at 6:15 p.m. ET. Tennessee holds a 6.5-point home advantage, and the over/under is 50.5 points. Additionally, No. 2 Georgia travels to face No. 12 Ole Miss at 7:30 p.m. ET, with the Bulldogs favored by 3.5 points and the total at 56.5.
The week begins on Thursday, November 5, with two games. FAU hosts UTSA, with the host team favored by 7 points and the total set at 71.5. Southern Miss welcomes James Madison, holding a 14.5-point home advantage with an over/under of 57.5. Friday, November 6, features three contests. SMU hosts Virginia Tech, with the Mustangs favored by 6 points and the total at 55.5. Illinois hosts Nebraska, with the Illini favored by 4.5 points and the total at 49.5. Arizona hosts TCU, with the Wildcats favored by 9.5 points and the total at 43.5.
Saturday also includes several other notable games. No. 14 LSU hosts No. 5 Alabama at 3:30 p.m. ET, with the Tigers favored by 5.5 points and the total at 52.5. No. 12 Ohio State hosts Oregon at the same time, with the Buckeyes favored by 7 points and the total at 52.5. Minnesota hosts No. 8 UCLA at noon ET, with the Bruins favored by 6.5 points and the total at 39.5. Texas Tech hosts West Virginia at 9:15 p.m. ET, with the Red Raiders favored by 17.5 points and the total at 63.5.
The Illinois versus Nebraska game on Friday is particularly interesting as both teams enter with 5-3 records. However, their recent form differs significantly. Nebraska, led by Bret Bielema, has won its last three games, while Illinois, under Matt Rhule, has lost its last three. Despite this trend, the Cornhuskers are favored by 4.5 points on the road. The over/under for this matchup is 49.5 points.
In the Nevada versus New Mexico game on Friday, the Lobos are favored by 10 points despite the Wolf Pack's strong head-to-head history. New Mexico has allowed no more than 18 points in any game this season, while Nevada has scored 20 or fewer in four of its eight games. The over/under for this contest is 38.5 points. Arizona, ranked No. 22, hosts TCU on Friday night. The Wildcats are favored by 9.5 points, with the total set at 43.5.
The Utah versus BYU game, known as the Holy War, marks the first time both schools have been ranked in the top 10 of the AP poll. This is only the fifth time both programs have been ranked heading into their head-to-head matchup. The Utes are favored by 5.5 points at home, and the over/under is 47.5 points.
Missouri hosts Texas on Saturday, with both teams coming off strong performances. Texas has rebounded from back-to-back losses with wins over Ole Miss and Mississippi State, while Missouri is unbeaten at home. The Longhorns are favored by 3 points on the road, and the over/under is 43.5 points. Minnesota hosts UCLA, with the Bruins leading the Big Ten standings at 8-0 overall and 5-0 in conference play. UCLA is favored by 6.5 points, and the over/under is 39.5 points.
The week concludes with a slate of evening games on Saturday, including the highly watched Notre Dame versus Miami contest. Both teams are looking to secure their positions for the College Football Playoff, with Notre Dame favored by 7.5 points at home. The over/under for this game is 55.5 points. Other late-night games include Ole Miss versus Georgia and Texas Tech versus West Virginia, both of which carry significant implications for conference titles and playoff seeding.
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